These cells are the characteristic feature of sickle cell anemia as well as hemoglobin S-thalassemia. Sickle cells, or drepanocytes, are elongated, crescent-shaped RBCs. Leptocytes are seen in people with thalassemia disorders and those with obstructive liver disease. Often called wafer cells, leptocytes are thin, flat cells with hemoglobin at the edge of the cell. While not as common, codoctyes may also be seen in people with sickle cell anemia, iron deficiency anemia, or lead poisoning. people who recently had their spleen removed ( splenectomy). ![]() Codocytes may appear in the following conditions:
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